Metabolic & Longevity Research

About Metabolic & Longevity Research at GenoPept

This range is defined by research field rather than chemical class. It brings together mitochondrial-derived peptides, short bioregulators, growth hormone fragments, coenzymes, enzyme inhibitors and nuclear receptor agonists, alongside liquid lipotropic solutions, each studied for how cells generate and spend energy, handle lipids, maintain mitochondria or respond to ageing.

Preclinical work spans AMPK and sirtuin signalling, NAD+ metabolism, mitochondrial integrity, senescent-cell clearance and fatty-acid oxidation. Buyers include UK university groups, contract research organisations and independent researchers.

Compounds in this range

Mitochondrial and longevity peptides

• MOTS-c – 16-amino-acid mitochondrial-derived peptide; studied for AMPK activation (10mg, 20mg, 40mg).
• Humanin 10mg – 24-amino-acid mitochondrial-derived peptide; studied in cytoprotection models (10mg).
• SS-31 (Elamipretide) – cardiolipin-binding tetrapeptide (elamipretide); studied in mitochondrial dysfunction models (10mg, 50mg).
• FOXO4-DRI – 46-amino-acid D-retro-inverso peptide disrupting FOXO4-p53; a senolytic tool (2mg, 10mg).
• Epitalon (Epithalon) – Ala-Glu-Asp-Gly bioregulator tetrapeptide; studied for telomerase expression (10mg, 40mg, 50mg).
• Thymalin 10mg – thymic polypeptide complex (Khavinson bioregulator); studied in immune-ageing models (10mg).

Growth hormone fragments and adipose-targeting peptides

• AOD-9604 – modified hGH 176-191 fragment with N-terminal tyrosine; studied in lipid-metabolism models (2mg, 5mg, 10mg).
• HGH Fragment 176-191 – native 16-amino-acid hGH fragment; the unmodified comparator in lipolysis assays (2mg, 5mg, 10mg).
• Adipotide (FTPP) – prohibitin-targeting pro-apoptotic peptidomimetic; studied in adiposity models (2mg, 5mg, 10mg).

Coenzymes, small molecules and cofactors

• NAD+ (Nicotinamide Adenine Dinucleotide) – redox coenzyme central to oxidative phosphorylation and sirtuin activity; used in ageing research (100mg, 250mg, 500mg, 1000mg).
• AICAR (Acadesine) – AMPK activator (acadesine); studied as a pharmacological exercise mimetic (50mg, 100mg).
• 5-Amino-1MQ – selective NNMT inhibitor; studied in adipocyte and NAD+ salvage models (5mg, 10mg, 20mg, 50mg).
• SLU-PP-332 5mg – pan-agonist of estrogen-related receptors; studied for mitochondrial biogenesis (5mg).
• L-Carnitine – fatty-acid transport cofactor; used in beta-oxidation assays (500mg, 600mg, 1000mg, 5000mg).
• Vitamin B12 10ml – cobalamin research solution; a one-carbon metabolism coenzyme (10ml).

Lipotropic research solutions (10 ml)

• Lipo-C Fat Metabolism Complex 10ml – lipotropics with B-vitamins; studied in hepatic lipid models (10ml).
• Lipo-B 10ml – lipotropic solution with vitamin B12 for combined cobalamin studies (10ml).
• Lipolytic Blend 10ml – riboflavin-based lipolytic solution; studied in adipocyte assays (10ml).
• Fat Blaster 10ml – lipotropic blend of methionine, inositol and choline-class compounds (10ml).
• Super Human Blend 10ml – B-vitamin cofactors, amino-acid derivatives and lipotropics combined (10ml).

Choosing between metabolic and longevity compounds for research

Begin with the pathway. For mitochondrial signalling, MOTS-c and humanin are the endogenous peptide tools, while SS-31 acts on the inner membrane. AICAR activates AMPK directly, NAD+ or 5-Amino-1MQ shift the NAD+ pool that sirtuins depend on, and SLU-PP-332 works through nuclear receptors.

For ageing biology, epitalon and thymalin are short bioregulators and FOXO4-DRI is a senolytic tool. AOD-9604 and HGH Fragment 176-191 are chosen together for modified-versus-native comparisons. The lipotropic solutions are liquids for hepatic and adipocyte lipid-handling studies. Our epitalon research guide and guide to Khavinson bioregulators cover the bioregulators in depth.

Purity, testing and Certificates of Analysis

Every batch GenoPept supplies is tested by Puralytix, an independent ISO/IEC 17025 laboratory, using HPLC for purity and LC-MS for identity, and released at 99% purity or higher. Each lot has a Certificate of Analysis showing purity and observed mass, opened from the View Certificate of Analysis button on the product page or the COA library. How to read a COA explains each field.

Ordering research peptides in the UK

Peptides come in 2mg to 50mg vials, small molecules up to 5000mg, and lipotropic lines as 10 ml solutions. Bulk boxes of 10 vials save 20 to 50%. Orders ship by tracked Royal Mail Special Delivery (£10), free on orders of £200 or more, with automatic basket discounts of 5% at £300, 10% at £500 and 15% at £1,000. Some lines ship on backorder, around 20 days from verified payment. Payment is by bank transfer or crypto; retail shipping is UK-only, wholesale export by quote. Before starting, read how to reconstitute research peptides, how to store research peptides, the UK legal position on research peptides.

Metabolic & Longevity Research FAQs

What is the Metabolic and Longevity research range?

It is GenoPept's collection of compounds for studying cellular energy metabolism, mitochondrial function, lipid handling and ageing biology: mitochondrial-derived peptides such as MOTS-c, SS-31, the bioregulators epitalon and thymalin, growth hormone fragments, small molecules such as NAD+, and lipotropic research solutions.

What is the difference between AOD-9604 and HGH Fragment 176-191?

Both are synthetic peptides from the C-terminal region of human growth hormone, residues 176 to 191, studied in preclinical lipid-metabolism models. HGH Fragment 176-191 is the unmodified 16-amino-acid sequence; AOD-9604 adds an N-terminal tyrosine and a disulfide bridge for stability. Researchers choose between them when comparing modified and native fragments.

How are metabolic and longevity research compounds tested?

Every batch is analysed by Puralytix, an independent ISO/IEC 17025 laboratory, using HPLC for purity and LC-MS for identity, and released at 99% purity or higher. Each lot has a Certificate of Analysis on the product page and in the COA library, whether peptide, small molecule or 10 ml research solution.

How should these compounds be stored and reconstituted?

Keep lyophilised peptides and powders at minus 20 degrees Celsius long term, or 2 to 8 degrees short term, protected from light, and reconstitute with bacteriostatic water or sterile diluent added down the vial wall, swirled and never shaken. The 10 ml research solutions are already liquid: store them refrigerated at 2 to 8 degrees.

Are metabolic and longevity research compounds for human use?

No. All products in this range, including the lipotropic and vitamin research solutions, are strictly for in-vitro laboratory research. They are not medicines or supplements, not for human or veterinary use, and not for diagnostic or therapeutic purposes. Buyers must comply with UK law and institutional ethics.

Research use only. Every product in this range is for in-vitro laboratory research only: not for human or veterinary use, not a medicine, not for diagnostic or therapeutic use. See our research use only policy.