GLP-1 Research Peptides

About GLP-1 Research Peptides at GenoPept

The compounds in this range are peptides acting on the receptors of the gut hormones glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), glucagon and amylin. Some are single-receptor GLP-1 analogues, others dual or triple agonists built on a GIP, glucagon or oxyntomodulin backbone. Almost all carry an albumin-binding fatty-acid side chain that extends half-life.

Preclinical research with these peptides explores appetite and energy-balance signalling, glucose-dependent insulin secretion, gastric emptying, hepatic lipid handling and, more recently, cardiovascular and renal models. They are bought by UK universities, contract research organisations and independent researchers running cell-culture or animal studies.

Compounds in this range

GLP-1 receptor agonists

• Semaglutide – 31-amino-acid GLP-1(7-37) analogue with a C18 diacid chain; the reference GLP-1 receptor agonist for energy-balance, glucose and receptor-signalling models. (5mg, 10mg, 15mg, 20mg, 30mg, 40mg, 50mg).
• Liraglutide – 31-amino-acid GLP-1(7-37) analogue with a C16 palmitoyl chain; a shorter-acting comparator to semaglutide. (5mg, 10mg, 30mg).

Dual and triple receptor agonists

• Tirzepatide – 39-amino-acid GIP-based dual GIP/GLP-1 receptor agonist studied in models of glucose regulation and adiposity. (5mg, 10mg, 15mg, 20mg, 30mg, 40mg, 50mg, 60mg, 70mg, 80mg, 90mg, 100mg, 120mg).
• Retatrutide – 39-amino-acid triple agonist at GIP, GLP-1 and glucagon receptors; studied for the contribution of glucagon activity in energy-expenditure and hepatic lipid models. (5mg, 10mg, 15mg, 20mg, 30mg, 40mg, 50mg, 60mg, 100mg).
• Mazdutide – 39-amino-acid acylated oxyntomodulin analogue; dual GLP-1/glucagon agonist studied in metabolic and liver models. (5mg, 10mg).
• Survodutide – 34-amino-acid acylated glucagon-based peptide; dual GLP-1/glucagon agonist studied in steatotic liver and energy-balance models. (5mg, 10mg).

Amylin analogues and blends

• Cagrilintide – long-acting acylated amylin analogue; dual amylin and calcitonin receptor agonist studied for satiety signalling independent of the GLP-1 pathway. (5mg, 10mg, 20mg).
• Cagrilintide + Semaglutide Blend – equal-mass co-formulation of cagrilintide and semaglutide for combined amylin and GLP-1 receptor studies. (5mg (2.5mg + 2.5mg), 10mg (5mg + 5mg)).
• Retatrutide + Cagrilintide Blend 10mg (5mg + 5mg) – equal-mass co-formulation of retatrutide with cagrilintide, combining four receptor targets in one vial. (10mg (5mg + 5mg)).

Choosing between GLP-1 peptides for research

The main variables are receptor profile, backbone and half-life; our semaglutide, tirzepatide and retatrutide comparison covers them in depth.

Single-target GLP-1 analogues suit mechanistic work needing a clean receptor readout; dual and triple agonists are chosen when the question concerns additive receptor activity. Cagrilintide and the blends let amylin signalling be studied alone or alongside GLP-1 activation.

Purity, testing and Certificates of Analysis

Every batch GenoPept supplies is tested by Puralytix, an independent ISO/IEC 17025 laboratory, using HPLC for purity and LC-MS for identity, and released at 99% purity or higher. Each lot has a Certificate of Analysis showing purity and observed mass, opened from the View Certificate of Analysis button on the product page or the COA library. How to read a COA explains each field.

Ordering research peptides in the UK

Vials run from 5mg to 120mg depending on the compound. Bulk boxes of 10 vials save 20 to 50%. Orders ship by tracked Royal Mail Special Delivery (£10), free on orders of £200 or more, with automatic basket discounts of 5% at £300, 10% at £500 and 15% at £1,000. Some lines ship on backorder, around 20 days from verified payment. Payment is by bank transfer or crypto; retail shipping is UK-only, wholesale export by quote. Before starting, read our GLP-1 research peptides guide, the semaglutide research guide, the UK legal position on research peptides.

GLP-1 Research Peptides FAQs

What are GLP-1 research peptides?

GLP-1 research peptides are synthetic analogues of the incretin hormone glucagon-like peptide-1, or engineered multi-agonists that add GIP, glucagon or amylin receptor activity. Most carry an albumin-binding fatty-acid chain. In research they are used to study energy balance, glucose regulation, gastric emptying and receptor signalling in cell-culture and animal models.

What is the difference between semaglutide and tirzepatide in research?

Semaglutide is a single-target GLP-1 receptor agonist built on the GLP-1(7-37) backbone. Tirzepatide is a 39-amino-acid GIP-based peptide that activates both GIP and GLP-1 receptors. Researchers comparing them ask whether added GIP activity changes outcomes in a model; retatrutide adds glucagon receptor agonism as a third target.

How are GenoPept GLP-1 peptides tested?

Every batch is analysed by Puralytix, an independent ISO/IEC 17025 laboratory, using HPLC for purity and LC-MS to confirm identity by molecular mass. Products are released at 99% purity or higher, and each lot has its own Certificate of Analysis on the product page and in the COA library, matched to the lot number on the vial label.

How should GLP-1 research peptides be stored and reconstituted?

Keep lyophilised vials at minus 20 degrees Celsius long term, or 2 to 8 degrees short term, protected from light. Reconstitute by adding bacteriostatic water or sterile diluent slowly down the vial wall and swirling gently; never shake, as acylated peptides can aggregate. Once reconstituted, keep at 2 to 8 degrees and use within your protocol's stated period.

Are GLP-1 research peptides for human use?

No. All GLP-1 research peptides sold by GenoPept are strictly for in-vitro laboratory research. They are not medicines, not for human or veterinary use, and not for diagnostic or therapeutic purposes. GenoPept does not provide dosing or administration advice for people. Researchers are responsible for compliance with UK law and institutional ethical requirements.

Research use only. Every product in this range is for in-vitro laboratory research only: not for human or veterinary use, not a medicine, not for diagnostic or therapeutic use. See our research use only policy.