What is Semax + Selank Blend?
Semax + Selank Blend is a co-formulated research preparation that combines two Russian-developed heptapeptides in a single 20 mg vial: Semax, an ACTH(4-10) analogue (Met-Glu-His-Phe-Pro-Gly-Pro), and Selank, a tuftsin-derived peptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro). GenoPept supplies this blend in the UK as a lyophilised powder for laboratory research. The published composition specifies a 20 mg total; the individual per-component split is not published, so no split is stated here.
Semax is studied mainly as a nootropic and neuroprotective peptide, while Selank is investigated for anxiolytic and immunomodulatory activity. The two are frequently co-investigated because their reported pathways are complementary, and the blend allows researchers to study them together in a single preparation.
Semax + Selank Blend research applications
Research relevant to the Semax + Selank Blend draws on the preclinical literature for each component. These model-based areas are listed for scientific context only.
- Cognition (Semax): studied in animal models of learning, attention and memory.
- Anxiety-like behaviour (Selank): examined in animal anxiety paradigms.
- Neurotrophic signalling: both peptides are reported to influence BDNF expression in model systems.
- Combined study: the blend is used to investigate the two peptides together in a single in-vitro or animal system.
Mechanism of action (preclinical)
The two peptides in this blend are reported to act through distinct but complementary preclinical mechanisms. Semax, an ACTH(4-10) analogue, is reported to up-regulate BDNF and TrkB signalling and to modulate dopaminergic and serotonergic systems without raising cortisol. Selank, derived from tuftsin, is reported to modulate GABAergic and serotonergic signalling, to influence enkephalin-degrading enzymes, and to exert immunomodulatory effects. Co-formulation lets researchers examine these pathways side by side. These are laboratory observations only.
Semax + Selank Blend product specifications
| Compound | Semax + Selank Blend |
|---|---|
| Also known as | Semax/Selank nootropic-anxiolytic blend |
| Sequence / class | Blend of two heptapeptides: Semax (Met-Glu-His-Phe-Pro-Gly-Pro) and Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) |
| CAS number | Semax 80714-61-0; Selank 129954-34-3 |
| Molecular weight | Semax 813.92 g/mol; Selank 751.87 g/mol |
| Form | Lyophilised powder |
| Available sizes | 20 mg total per vial |
| Purity | Batch-specific; see applicable report |
| Verification | Batch-specific; see applicable report |
| Storage (unopened) | –20 °C long term, protected from light |
| Intended use | In-vitro laboratory research only |
Available sizes
- Semax + Selank Blend 20mg vial
Semax + Selank Blend is offered in the vial sizes listed above for UK research laboratories. Wholesale boxes of 10 vials are available through GenoPept for teams running larger studies, with tiered savings on bulk orders. See the bulk and wholesale page for details.
Reconstitution, handling and storage (laboratory)
Semax + Selank Blend is supplied as a lyophilised (freeze-dried) powder in a sealed sterile glass vial with a black cap. For laboratory reconstitution, add bacteriostatic water or a suitable sterile diluent slowly down the inner vial wall, then swirl gently until dissolved. Never shake the vial, as agitation can shear the peptide.
Store unopened vials at –20 °C for long-term stability, or at 2–8 °C for short periods, protected from light. After reconstitution, keep the solution at 2–8 °C and use it within the window stated in the laboratory protocol. See the GenoPept guides on how to reconstitute research peptides and how to store research peptides.
Quality assurance and Certificate of Analysis
Purity and identity results are batch-specific. Consult the applicable supplied report for its results and methods; confirm the batch covers current stock and verify the laboratory’s accreditation scope directly.
The matching Certificate of Analysis (COA) is available from the “View Certificate of Analysis” button on this page, and the full library is published at the GenoPept COA certificates page. Learn more about what a Certificate of Analysis shows and the UK legal status of research peptides.
Related research compounds
- Semax — the nootropic ACTH(4-10) component on its own.
- Selank — the tuftsin-derived anxiolytic component on its own.
- NA-Semax Amidate — a stabilised Semax analogue for comparison.
- DSIP — a neuropeptide studied in sleep and stress-response research.
Semax + Selank Blend frequently asked questions
What is the Semax + Selank Blend used for in research?
The Semax + Selank Blend is used in laboratory research to study the two peptides together, combining Semax’s nootropic and neuroprotective research profile with Selank’s anxiolytic and immunomodulatory profile. It is used in cell-culture and animal models for combined investigation and is supplied strictly for research, not for human use, diagnosis or therapy.
How is the Semax + Selank Blend supplied and what is its purity?
Purity and identity results are batch-specific. Consult the applicable supplied report for its results and methods; confirm the batch covers current stock and verify the laboratory’s accreditation scope directly.
What is the per-component split in the blend?
The published specification for this product states a 20 mg total per vial. The individual split between Semax and Selank is not published, so GenoPept does not state a per-component figure. Researchers requiring exact per-peptide quantities should refer to the batch Certificate of Analysis supplied with the order.
How should the Semax + Selank Blend be stored?
Store the unopened blend vial at –20 °C for long-term stability, or at 2–8 °C briefly, protected from light. After reconstitution with bacteriostatic water or sterile diluent, keep the solution at 2–8 °C and use it within the window given in the laboratory protocol to preserve the integrity of both peptides.
Is the Semax + Selank Blend for human use?
No. The Semax + Selank Blend from GenoPept is a research chemical supplied for in-vitro laboratory research only. It is not a medicine, not for human or veterinary use, and not intended for diagnostic or therapeutic purposes. All handling should be carried out by qualified personnel in a controlled laboratory environment in line with UK research guidance.
Research use only. This product is supplied for in-vitro laboratory research only. It is not for human or veterinary use, is not a medicine, and is not intended for diagnostic or therapeutic use. Handling should be carried out only by qualified personnel in an appropriate laboratory setting.
Research guides: Semax and Selank Research Guide




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