What is Lipo-B 10ml?
Lipo-B 10ml is a proprietary liquid research solution that pairs lipotropic compounds with vitamin B12 (cobalamin) in a 10 ml multi-dose vial, supplied for laboratory research on lipid metabolism and methylation. It is a class-defined mixture rather than a single compound: lipotropic agents in the research literature are typically methyl-donor and phospholipid-precursor molecules of the methionine, inositol and choline type, and cobalamin is the cofactor for methionine synthase, the enzyme that links the folate and methionine cycles.
The exact quantitative formula of Lipo-B is not published by GenoPept, so this page describes component classes and does not assert a specific composition. Lipo-B is the narrower counterpart of Lipo-C, which adds a broader B-vitamin set, and UK laboratories choose between them depending on whether the study isolates the cobalamin variable.
Lipo-B 10ml research applications
Methylation and homocysteine metabolism
Because vitamin B12 is required to remethylate homocysteine to methionine, Lipo-B is used in cell-culture models that measure S-adenosylmethionine, homocysteine and global DNA methylation under different methyl-donor supply.
Hepatic lipid export
Lipotropic compounds are studied for their influence on phosphatidylcholine synthesis and very-low-density lipoprotein assembly in hepatocytes, and Lipo-B allows both the lipotropic and cobalamin inputs to be varied together.
Fatty liver and metabolic models
Rodent models of diet-induced hepatic steatosis are a common setting for lipotropic research, with liver triglyceride and lipid-droplet markers as readouts.
Comparative formulation research
Lipo-B is used alongside vitamin B12 alone and Lipo-C to separate the contribution of each class in a combined solution.
Mechanism of action (preclinical)
Lipotropic compounds act on hepatic lipid handling through phospholipid synthesis in preclinical models: choline-type molecules supply phosphatidylcholine directly, while methionine-type molecules feed the S-adenosylmethionine pool that converts phosphatidylethanolamine to phosphatidylcholine. Adequate phosphatidylcholine is needed to package triglyceride for export from the liver.
Vitamin B12 enters the same pathway as the cofactor for methionine synthase, which regenerates methionine from homocysteine using 5-methyltetrahydrofolate, and for methylmalonyl-CoA mutase in odd-chain fatty-acid catabolism. Lipo-B is therefore investigated as a pathway-level combination, with no single receptor target, in cell and animal models of lipid and one-carbon metabolism.
Lipo-B 10ml product specifications
| Specification | Detail |
|---|---|
| Product type | Lipotropic research solution with vitamin B12 (proprietary formula) |
| Form | Liquid research solution in a sealed multi-dose glass vial |
| Volume | 10 ml |
| Key components (class-level) | Lipotropic compounds of the methionine, inositol and choline class with vitamin B12 (cobalamin); exact composition not published |
| Verification | Component identity by LC-MS and purity by HPLC, Puralytix (ISO/IEC 17025), batch COA |
| Storage | 2–8 °C, protect from light, do not freeze |
| Intended use | In-vitro laboratory research only |
Available sizes
- Lipo-B 10 ml multi-dose research solution vial
Lipo-B is supplied in a single 10 ml vial size from UK stock. Boxes of 10 vials save 20 to 50% through the bulk and wholesale page.
Reconstitution, handling and storage (laboratory)
Lipo-B is supplied as a 10 ml multi-dose research solution and does not require reconstitution. Store unopened vials at 2 to 8 °C, protected from light, and do not freeze; freezing can cause components to precipitate. Allow the vial to reach room temperature before drawing so that volumes are accurate.
Swab the stopper before each draw and use a fresh sterile needle every time to protect the multi-dose seal. Record the first-puncture date on the label, return the vial to the refrigerator between uses, and discard it at the end of the period set by your protocol or if the solution changes colour, turns cloudy or shows particulates. Cobalamin solutions are light-sensitive, so keep the vial in its carton. General guidance is in the storage guide on the site.
Quality assurance and Certificate of Analysis
Every batch of Lipo-B 10ml supplied by GenoPept is tested by an independent UK third-party laboratory (Puralytix, ISO/IEC 17025 accredited). Testing confirms the identity of the declared components by LC-MS and checks purity of the active compounds by HPLC. The batch Certificate of Analysis (COA) is available through the “View Certificate of Analysis” button on this page, and the full library is published at genopept.co.uk/coa-certificates.
Each vial is sealed, batch-identified with lot number and expiry date, and dispatched by tracked Royal Mail Special Delivery within the UK (free on orders of £200 or more). Read what a Certificate of Analysis shows to interpret the report.
Related research compounds
- Lipo-C Fat Metabolism Complex 10ml: the broader lipotropic and B-vitamin complex for comparison.
- Vitamin B12 10ml: the cobalamin component studied on its own.
- Lipolytic Blend 10ml: a riboflavin-containing lipolytic research solution.
- L-Carnitine: a fatty-acid transport cofactor used in the same metabolic models.
Lipo-B 10ml frequently asked questions
What is Lipo-B used for in research?
Lipo-B is used as a combined lipotropic and vitamin B12 research solution in laboratory studies of hepatic lipid metabolism, methylation and one-carbon pathways. Researchers use it in hepatocyte cultures and rodent models to examine how lipotropic compounds and cobalamin together influence phosphatidylcholine synthesis, homocysteine remethylation and lipid export. It is supplied for in-vitro research only.
What does lipotropic mean in research?
In preclinical research, a lipotropic compound is one that promotes the export or mobilisation of fat from liver tissue rather than its accumulation. The term covers methyl-donor and phospholipid-precursor molecules of the methionine, inositol and choline type. It describes a class of activity observed in cell and animal models, not a claim about effects in people.
How is Lipo-B supplied and verified?
GenoPept supplies Lipo-B as a 10 ml multi-dose liquid research solution in a sealed, batch-identified glass vial. The exact quantitative formula is proprietary, so the composition is described at class level as lipotropic compounds with vitamin B12. Each batch is tested by an independent ISO/IEC 17025 laboratory and the Certificate of Analysis is linked from this page.
How should Lipo-B be stored in the laboratory?
Store Lipo-B at 2 to 8 °C, protected from light, and do not freeze. Cobalamins degrade on prolonged light exposure, so keep the vial in its carton between draws. After first puncture, date the label, swab the stopper before each draw with a fresh sterile needle, and keep the vial refrigerated. Discard if the solution becomes cloudy or the colour changes.
Is Lipo-B for human use?
No. Lipo-B is sold strictly for in-vitro laboratory research. It is not a medicine, supplement or weight-management product, is not for human or veterinary use, and is not intended for diagnostic or therapeutic use. Purchasers confirm they are buying for research and agree to the research use only terms before ordering.
Research use only. This product is supplied for in-vitro laboratory research only. It is not for human or veterinary use, is not a medicine, and is not intended for diagnostic or therapeutic use. See the research use only policy for full terms.
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